Axolotl DualGraft™
Indicated as a wound covering
and structural barrier
Processed through minimally
manipulated techniques designed to
retain the qualities of the native ECM
Simplified application | Processed with
epithelial surfaces facing outwards
NATURAL
EFFICIENT
EFFECTIVE
Evidence supporting the use of Amnion
The Extracellular Matrix (ECM)
3-D structure & essential component in all human tissues that aids in: Cellular adherence | Tissue anchoring
Cellular signaling | Recruitment of cells1
ECM contributes to:
Formation of granulation tissue | Germination of new blood vessels | Maintaining viability of new tissue2
Human Amniotic Membrane (hAM)
Surgical recommendations are for application of hAM epithelial side against the wound3,4,5
Axolotl DualGraft™ Application
Open box, remove outer
tray. Open the outer tray
and remove the inner tray
(the inner tray is sterile and
may be placed onto the
sterile field). Open the inner
tray and remove the Axolotl
DualGraft package.
Using sterile scissors, cut
open the package and
remove Axolotl DualGraft.
Apply Axolotl DualGraft
directly to the area of
interest. Secure Axolotl
DualGraft with sutures,
glue, or steri-strips if
desired, based on physician
preference. Cover graft
with a wide meshed nonadherent dressing (Adaptic).
Use a bolster dressing such
as gauze if necessary to fill
dead space.
STORAGE
Stored at ambient temperature
PRESERVATION METHOD
Terminal irradiation gives the membrane a
5-year shelf life.
CONTAINS ESSENTIAL PROTEINS
& GROWTH FACTORS
Proteins found in Axolotl DualGraft™ include:
• Collagen I, Ill, IV, V and VII
• Fibronectin
SKU
DESCRIPTION
SIZE
Q CODE
ADG12
Axolotl DualGraftTM
1X2
Q4332
ADG22
Axolotl DualGraftTM
2X2
Q4332
ADG24
Axolotl DualGraftTM
2X4
Q4332
ADG44
Axolotl DualGraftTM
4X4
Q4332
ADG46
Axolotl DualGraftTM
4X6
Q4332
ADG48
Axolotl DualGraftTM
4X8
Q4332
ADG1010
Axolotl DualGraftTM
10X10
Q4332
Axolotl DualGraft has received a positive
recommendation from the FDA Tissue
Review Group (TRG) and is manufactured
in an AATB accredited facility
References: 1-Diller, R.B.; Tabor, A.J. The Role of the Extracellular Matrix (ECM) in Wound Healing: A Review. Biomimetics 2022, 7, 87. 2-Fitriani, N.;Wilar, G.; Narsa, A.C.; Mohammed, A.F.A.; Wathoni,
N. Application of Amniotic Membrane in Skin Regeneration. Pharmaceutics 2023, 15, 748. 3-Odet S, Louvrier A, Meyer C, Nicolas FJ, Hofman N, Chatelain B, Mauprivez C, Laurence S, Kerdjoudj H,
Zwetyenga N, Fricain J-C, Lafarge X, Pouthier F, Marchetti P, Gauthier A-S, Fenelon M and Gindraux F (2021) Surgical Application of Human Amniotic Membrane and Amnion-Chorion Membrane in
the Oral Cavity and Efficacy Evaluation: Corollary With Ophthalmological and Wound Healing Experiences. Front. Bioeng. Biotechnol. 9:685128. doi: 10.3389/fbioe.2021.685128. 4–Dua, H et.al. The
Amniotic Membrane in Ophthalmology. Survey of Ophthalmology 2004, 49 (1), 51-77. 5-Sippel, K; Ma, J & Foster, C Amniotic membrane surgery. Current Opinion in Ophthalmology 2001, 12:269–281.