High purity Type-I Collagen: Helicoll is a patented reconstituted bioactive collagen
sheet, free of immunogenic proteins, lipids, and elastin. The native structure of collagen
is not altered or cross-linked which maintains its high bioactivity.

Faster Healing: Collagen phosphorylation attracts cells, regenerates issue, and stimulates blood
capillaries/granulation tissue.

Innovative Technology: Better than intact issue-based membranes like an amnion, intestinal wall,
urinary bladder etc. which contain >15% elastin that is recently discovered to be carcinogenic.

Pain Control: Effectively reduces pain.

Easy Applicaton: No washing needed prior to use. The overall clinical usage of Helicoll is
simple and can easily be cut, sutured or stapled.

Cost-Effective: Accelerated wound healing and issue remodeling with minimal applications
reduce the treatment cost.

Contra-Indications: Helicoll is derived from a bovine or ovine source and should not be
used in parents with known sensitivity to such material. This device is not
indicated for third-degree burns.

Precautions: Do not resterilize. Helicoll is sterile if the package is dry, unopened and
undamaged. Do not use if the package seal is broken. The device must be used prior to
the expiration date. Discard all open Helicoll and any unused portions. Helicoll is
available by medical prescription only.

Storage: Helicoll should be stored in a clean, dry location at room temperature.

Sterilization: Helicoll has been sterilized with ethylene oxide.

Shelf Life: Helicoll shelf life is 3 years.